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By S. Copper. Drake University.

If a gorilla can be almost completely vegan (some eat termites and ants purchase albuterol 100mcg online, along with whatever bugs are on the plant they are eating) and survive without consuming animal products (and dairy) for their strong muscles and bones cheap 100 mcg albuterol visa, then so can I. The second thing I do when confused is look at what healthy aging cultures eat, like the Okinawans, Sardinians, Nicoyans, Hun- zas, Abhkasians, Vilcabambans, Seventh Day Adventists, Tarahu- mara Indians, or the cultures in the “Cold Spots” or “Blue Zones” of the world. You see very similar dietary patterns: They eat local fresh fruit and vegetables; a staple, unrefined grain (starch) usu- ally; some beans, lentils or root vegetables; and maybe some nuts and seeds. The animal products they eat are generally more of a condiment than a big part of their plate. It may not be eaten every day, maybe only on special occasions or once or twice per week— and it is usually a free-ranged, grass-fed animal eating local vegeta- tion (with an anti-inflammatory fat profile) and lean overall. This is a much different way of eating than the typical consumer of the Western diet. About fifteen or so years ago, I became a vegetarian, and around ten or more years ago, I became what I call a “sloppy” vegan. A vegetarian eats plant foods but can also, depending on the type of vegetarian, eat eggs (ovo-) or dairy products (lacto-). I call myself a “sloppy” vegan because I still have leather shoes, once a month or so I might have some type of dairy food or maybe something with eggs in it. I might have veg- etable soup at a restaurant that might be made with chicken broth. I don’t go out and buy animal foods for my home use, nor do I go out and order animal foods. I would say that I am a 99 percent-plus vegan; “sloppy” is a pretty good description! Once you start, it grows on you, and aspects of it become more important to you and you continue to change. Health and Weight Control Being a Vegetarian Before I describe the benefits of vegetarianism on weight con- trol, I want to make it clear that I am talking about whole-food vegetarians, eating the majority of their diet as vegetables, fruit, beans, nuts and seeds, whole grains and minimal or no refined or processed foods. There is nothing worse for the cause of encour- aging plant-based diets than a “loud” vegetarian who is eating refined-grain products, rich in fats and added sugar; processed vegetarian foods; and virtually no vegetables and fruit—one who looks shriveled up, pale, and has to have his or her caffeine fix in order to walk. Or, a vegetarian who is overweight, eating all kinds of refined, sweet-fat-enriched flour “animal-free” foods. Please, please, my vegetarian brothers and sisters—eat whole, unrefined plant foods with tons of vegetables, fruit, beans, nuts, seeds, and moderate amounts of whole grains. Cor- dain, the author of The Paleo Diet, so aptly calls these types of veg- etarians, “breaditarians. The easy access to food (calories) makes our survival- oriented “thrifty genes” work overtime, storing excess calories as fat to protect us from when we don’t have enough calories, which in modern, urbanizing life is usually never. Thus, modern man has too many calories at his fingertips and in frequencies that we never had during our evolution. There is room for debate on the use of nuts and seeds in weight-reduction programs as part of your daily diet. There is no problem eating raw nuts or seeds in a weight-reduction program if you have some control and replace animal foods with them. Raw nuts have good fats and provide pro- tein, fiber, and provide a degree of satiety. Also, some fat may help prevent gall bladder disease and improve vitamin absorption on a low-fat, plant based weight-reducing diet. The problem is many people eat handfuls of salted and roasted nuts (instead of raw), which have significant amounts of fat as well as salt. So I am al- ways cautious in recommending nut and seed consumption, which are inherently very nutritious and good foods. Remember, fat has two-and-a-half times the calories of a carbohydrate or protein per gram! Processed foods are not good for weight control for obvious reasons: They are calorie dense from added fats and oils and calo- rie sweeteners (sugars) and low in fiber and beneficial nutrients because the grains are refined. Animal foods, especially factory- farmed animal foods, and dairy products are very calorie-dense foods and generally don’t have beneficial fatty acid profiles and increase inflammation. To do this, you need to eat the foods with the highest nutrients per calorie (nutrient density) and the lowest amount of calories per weight (calorie density) that are packed with the most amount of protective phytonutrients (vitamins, minerals, antioxi- dants, phenolic compounds, etc. This formula is found in a plant- strong diet containing lots of vegetables, fruit, beans, some whole grains, and raw nuts and seeds. I am a vegetarian because of health, ecology, kindness to ani- mals, and spiritual reasons. Getting over the craving for meat is easier than dairy products, caffeine, or sugar. I allowed myself one hamburger a week, and that was the only meat I ate for several years. It is a personal journey, but this journey will change you and the planet for the better.

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In 90% of cases the tumours is in adrenal medulla while in 10% the tumour is extra-adrenal affecting the sympathetic chain albuterol 100mcg visa. Beside the clinical criteria of this tumour order 100 mcg albuterol amex, serum and urinary catecholamine assay will confirm the diagnosis. The tumour is extremely sensitive to X-ray contrast media, on exposure it will secrete a huge amount of catecholamine with fatal outcome. So, in hypertensive patient if pheochromocytoma is expected, this should be excluded first; by catecholamine assay before the patient is subjected to the contrast media. Treatment is by hypotensive drugs having A and B-adrenergic blocking properties as labetalol and carvedilol. Abdominal paracentesis, vigorous diuretic therapy and bleeding- especially gastrointestinal-are known precipitating factors. Laboratory assessment will show a progressive increase in serum creatinine and blood urea. Mainly those with potentially reversible acute liver disease and those awaiting orthotopic liver transplantation. As protein in urine decreases the surface tension, it causes frothy urine which may be observed by some patients (bile salts and detergents used in toilets do the same). Dipstick is a plastic strip, attached to it is a paper impregnated with chemical substance (tetrabromophenol) which is normally yellow in colour and changes according to amount of protein in urine (0, +, ++, +++). Proteinuria detected by dip stick test should be confirmed by collecting the 24 hours urine and testing for quantity of proteinuria using chemical methods. Definitions: • Proteinuria is a secretion of an abnormal amount of protein in urine. Most of this protein is albumin and Tamm Horsfall protein with smaller amounts of immunoglobulins. False negative proteinuria is observed when protein excretion is mainly Bence Jones proteinuria and when urine is very diluted. Abnormality in permeability of the glomerular basement membrane because of glomerular disease or abnormal glomerular hemodynamics. Functional proteinuria: There is no organic change in the kidney tissue: it is usually less than 1 gm/d and is reversible. Possibly, it is due to hemodynamic changes or to minor glomerular disease which are reversible. Chronic interstitial nephritis such as bacterial (pyelonephritis), gouty nephropathy, analgesic nephropathy or nephrolithiasis. Tubular proteinuria such as Fanconi syndrome, heavy metal intoxication (lead, cadmium), multiple myeloma, hypokalaemic nephropathy, polycystic kidney disease and medullary cystic kidney disease. Primary glomerular disease: refers to all types previously discussed under glomerulonephritis. Characterization of proteinuria: After diagnosis of proteinuria by dip stick test, it should be confirmed by quantitative estimation of 24 hours proteinuria. Further assessment may include electrophoresis or immunoelectrophoresis to determine the type of abnormal protein excreted. Kidney function tests: serum creatinine, creatinine clearance, electrolytes (Na, K, Ca, Po4). Examination of the kidney for its size, state of parenchyma, the presence of stone, back pressure change or pyelonephritic changes. Investigations to discover malignancy which could be the etiologic cause of proteinuria e. Renal biopsy will give the final answer for the diagnosis of the kidney lesion causing proteinuria. In gross hematuria, urine looks red if alkaline, but brown or coca-cola like if urine is acidic due to denaturation of the hemoglobin. Proteinuria is present in most cases of glomerular hematuria but not in cases of non glomerular hematuria. Blood clots indicate non-glomerular bleeding and can be associated with pain & colic. IgA nephropathy, mesangial proliferative glomerulonephritis or crescentic glomerulonephritis); or secondary glomerulonephritis i. Renal infection: Pyelonephritis (especially with papillary necrosis) or renal tuberculosis. Renal neoplastic disease: Renal cell carcinoma, transitional cell carcinoma of the renal pelvis and others. Renal vascular disease: Renal infarction, renal vein thrombosis or malignant hypertension. First exclude haemoglobinuria and myoglobinuria since both of them can also cause positive dipstick test for haematuria. In case of myoglobinuria, clinical examination may show manifestations of muscle disease and the examination of urine by immunoelectrophoresis may show myoglobin.

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Many other types of arboviral Arnold Chiari malformation See Chiari mal- encephalitis occur throughout the world albuterol 100mcg overnight delivery. It causes West Nile which essential oils or other scents are inhaled to encephalitis generic albuterol 100mcg without a prescription, also known as West Nile fever. When archaea A unique group of microorganisms that stimulated, the arrector pili contracts and causes are called bacteria (Archaeobacteria) but are genet- the hair to become more perpendicular to the skin ically and metabolically different from all other surface, thereby erecting the hair (causing the hair known bacteria. The arrector pili muscle plays a survivors of an ancient group of organisms that key role in forming goose bumps. With an arcus senilis A cloudy opaque arc or circle arrhythmia, the heartbeats may be irregular or too around the edge of the eye, often seen in the eyes of slow (bradycardia), too rapid (tachycardia), or too the elderly. When a single heartbeat occurs earlier than normal, it is called a premature contraction. Examples of atrial arrhythmias include atrial fibril- arginine An essential amino acid and a key com- lation, atrial flutter, and paroxysmal atrial tachycar- ponent of protein. Arginine is available in turkey, arrhythmia, ventricular An abnormally rapid chicken, and other meats, and as L-arginine in sup- heart rhythm that originates in the lower chambers plements. Ventricular arrhythmias phate synthetase have arginine deficiency syndrome; include ventricular tachycardia and ventricular fib- adding arginine to their diets permits normal rillation. Caused by long-term use of silver salts or arterial anastomosis A joining of two arteries. The oxygenated hemoglobin (oxyhemo- globin) makes the blood in arterioles (and arteries) arthritis Inflammation of a joint. There are more than arteriosclerosis Hardening and thickening of 100 types of arthritis. Arteriosclerosis leads to spondylitis; arthritis, degenerative; arthritis, heart attacks and strokes, as well as to peripheral gouty; arthritis, Lyme; psoriatic arthritis; arthri- vascular disease. Arteriosclerosis can be catego- tis, Reiter; arthritis, rheumatoid; arthritis, rized as atherosclerosis, medial calcification, hyper- spondylitis; gout; lupus; pseudogout. See also atherosclerosis; heart attack; stroke; peripheral arthritis, degenerative A type of arthritis vascular disease. Degenerative arteriosclerotic aneurysm See aneurysm, arthritis is the most common form of arthritis, usu- arteriosclerotic. The muscle aching of polymyalgia rheumatica is arthritis, Reiter The joint component of a syn- seen in one-fourth of patients with cranial arteritis. This can cause serious deficiency of oxygen supply to the tis- arthritis, rheumatoid An autoimmune disease sues that are normally supplied by these arteries. Deficient oxygenation of the eyes or brain can lead Rheumatoid disease can also involve inflammation to impaired or double vision, blindness, or stroke. The disease is detected by a biopsy of organs of the body, rheumatoid arthritis is referred an artery and treated with high dose cortisone- to as a systemic illness. Also known as temporal arteri- tis is a chronic illness, patients may experience long tis and giant cell arteritis. Treatment artery A blood vessel that carries blood, rich in includes antibiotic medications and surgical oxygen, away from the heart to the body. Also known as pyarthosis and suppurative genated hemoglobin (oxyhemoglobin) in arterial arthritis. See also aorta; carotid artery; ophthalmic artery; radial artery; arthritis, spondylitis A form of arthritis that splenic artery; vertebral artery. An arthroscope is fitted arthritis, systemic-onset juvenile rheumatoid with a miniature camera, a light source, and preci- A form of joint disease in children whose systemic sion tools at the end of flexible tubes. The arthritis itself may not be arthroscopy A surgical technique in which a immediately apparent, but in time it surfaces and tube-like instrument is inserted into a joint to may persist after the systemic symptoms are long inspect, diagnose, and repair tissues. Also known as systemic-onset chronic arthri- commonly performed in patients with diseases of tis or Still’s disease. See also arthritis, systemic- articulation 1 In medicine, the joint where onset juvenile rheumatoid. Articulation disorders often involve substi- needle and syringe are used to drain fluid from the tution of one sound for another, slurring of speech, joint. For certain condi- tions, medication is put into the joint after fluid artificial heart A human-made heart. The needle is then removed, and a band- cial heart is a mechanical pump that is used to age or dressing is applied over the entry point. Joint replace a damaged heart temporarily or perma- fluid can be examined to determine the cause of the nently. Arthrocentesis can be helpful in reliev- artificial insemination A procedure in which a ing joint swelling and pain. Also known as joint fine catheter (tube) is inserted through the cervix into aspiration. The purpose of this relatively simple procedure is to arthrogryposis Joint contractures that develop achieve fertilization and pregnancy. In normal embryonic artificial insemination by donor A procedure in development, joints can be seen moving by 8 weeks which a fine catheter (tube) is inserted through the of gestation. This motion of joints is essential to the cervix into the uterus to directly deposit a sperm sam- proper development of the joints and structures ple from a donor other than the woman’s mate.

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It is the most frequent cause of death from poisoning (see Ta- ble 13-2 for threshold limit values) purchase albuterol 100 mcg on line. Carbon monoxide competes for and combines with the oxygen-binding site of hemoglobin to form carboxyhemoglobin generic 100mcg albuterol with visa, resulting in a functional anemia. The binding affinity of carbon monoxide for hemoglobin is 220 times higher than that of oxygen itself. Carboxyhemoglobin also interferes with the dissociation in tissues of the remaining oxyhemoglobin. Smokers may routinely exceed normal carboxyhemoglobin levels of 1% by up to 10 times. Symptoms include headache, dizziness, nausea, vomiting, syncope, seizures, and at carboxyhemoglo- bin concentrations above 40%, a cherry-red appearance and coma. Populations at special risk include smokers with ischemic heart disease or anemia, the elderly, and the developing fetus. Sulfur dioxide is a colorless, irritant gas produced by the combustion of sulfur-containing fuels (see Table 13-2 for threshold limit values). Nitrogen dioxide is an irritant brown gas produced in fires and from decaying silage. It also is produced from a reaction of nitrogen oxide (from auto exhaust) with O2 (see Table 13-2 for threshold limit values). Nitrogen dioxide causes the degeneration of alveolar type I cells, with rupture of alveolar capillary endothelium. Acute symptoms include irritation of eyes and nose, coughing, dyspnea, and chest pain. Severe exposure may in 1–2 hours result in pulmonary edema that may subside and then recur more than 2 weeks later. Ozone is an irritating, naturally occurring bluish gas found in high levels in polluted air and around high-voltage equipment (see Table 13-2 for threshold limit values). Ozone irritates mucous membranes and can cause decreased pulmonary compliance, pul- monary edema, and increased sensitivity to bronchoconstrictors. Chronic exposure may cause decreased respiratory reserve, bronchitis, and pulmonary fibrosis. Hydrocarbons are oxidized by sunlight and by incomplete combustion to short-lived aldehydes such as formaldehyde and acrolein; aldehydes are also found in, and can be released from, cer- tain construction materials. Inhalation of particulates can lead to pneumoconiosis, most commonly caused by silicates (sil- icosis) or asbestos (asbestosis). Bronchial cancer and mesothelioma are associated with asbestos exposure, particularly in conjunction with cigarette smoking. Particulates adsorb other toxins, such as polycyclic aromatic hydrocarbons, and deliver them to the respiratory tract. Aliphatic and halogenated aliphatic hydrocarbons include fuels and industrial solvents such as n-hexane, gasoline, kerosene, carbon tetrachloride, chloroform, and tetrachloroethylene (see Table 13-2 for threshold limit values). Neural effects, such as memory loss and peripheral neuropathy, predominate with chloroform and tet- rachloroethylene exposure. Hepatotoxicity (delayed) and renal toxicity are common with carbon tetrachloride poisoning. Carcinogenicity has been associated with chloroform, carbon tetrachloride, and tetrachloro- ethylene. All of these effects may be mediated by free radical interaction with cellular lipids and proteins. Chronic exposure can result in severe bone marrow depression, resulting in aplastic anemia and other blood dyscrasias. It can cause fatigue and ataxia at relatively low levels (800 ppm), and loss of consciousness at high levels (10,000 ppm). As insecticides, these agents are preferred over chlorinated hydrocarbons because they do not persist in the environment. Atropine reverses all muscarinic effects but does not reverse neuromuscular activation or paralysis. It often is used as an adjunct to atropine (may reverse some toxic effects); however, it is most effective in parathion poisoning. Carbamate insecticides include, among others, carbaryl, carbofuran, isolan, and pyramat. Carbamate insecticides produce toxic effects similar to those of the phosphorus-containing insecticides. Generally, the toxic effects of carbamate compounds are less severe than those of the organophosphorus agents because carbamoylation is rapidly reversible. Pralidoxime therapy is not an effective antidote because it does not interact with carbamylated acetylcholinesterase. These agents inactivate the sodium channel of excitable membranes, resulting in repetitive neuronal firing with paresthesias, tremor, or seizures. Poisoning is characterized by salivation, vomiting, muscle weakness, seizures, and respiratory arrest; it can be treated with anticonvulsants and agents for symptomatic relief (see Chapters 2 and 5). Treatment consists of prompt gastric lavage; administration of cathartics and adsorbents benefits some victims.

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